I also think that Goodell is all over this situation. I think he has been in contact with the Mannings and has spoken to their doctors. He does not want something to happen on the field to Manning. That would be unforgivable for the NFL and a PR nightmare that would take years to overcome, if ever.
I am sure that they will evaluate every pimple on his @ss to be a sure as they can be that he will hold up.