Bear with me as this is an attempt at a completely serious post.
I used to play Madden with a regular group of guys I had met online when Madden first went live with online play, which was back in 2003.
We were all proponents of playing the game the way it was meant to be played, as straight/simulation type of game as possible. That meant no bs running up the score, or going for it on every single 4th and long, etc.
When you play online long enough you can pretty much tell who is going to respect their opponent, and who is going to go full douchebag and run up the score on you.
If you want a taste of what you're going to get, then by all means go online and play any random dude, more times than not they will most likely 'cheese' the **** out of you with garbage plays and using every single exploit to their advantage.
But I digress. Find a playbook that fits your play style and learn it. Also very importable to pick a set of plays to audible to when someone looks like they are showing run but you think they will pass, etc.
If I still had this game I would love to play against of you guys, but I gave up Madden because it lent itself to drinking very heavily during games, which made it a lot of fun, but I paid the price the next day. I used to average drinking a beer per quarter if I recall correctly.