I disagree. PIT's defense has been perennially known for this run stopping ability, and pass rush. They're secondary has been as up and down as any team's in the league. and right now, they got injuries and age to make up for.
I'd take Manning. Running on PIT might still be tough, but don't think it's too much to ask to expect Peyton to throw 3 TDs.
I don't disagree, but the colts are Playing a ton of rookies. They have 30 on the roster I believe